O-Linked L-Fucose Is Present in Desmodus rotundus Salivary Plasminogen Activator
نویسندگان
چکیده
منابع مشابه
Thrombolytic properties of Desmodus rotundus (vampire bat) salivary plasminogen activator in experimental pulmonary embolism in rats.
rDSPA alpha 1 (recombinant Desmodus salivary plasminogen activator alpha 1) is a recombinant protein corresponding to a natural plasminogen activator from the vampire bat Desmodus rotundus. The thrombolytic properties of rDSPA alpha 1 and tissue-type plasminogen activator (t-PA) were compared in a rat model of pulmonary embolism. Whole blood clots, produced in vitro and labeled with 125I-fibrin...
متن کاملCoronary Thrombolysis With Desmodus Salivary Plasminogen Activator in Dogs
25. Thomas GR, Thibodeaux H, Bennett WF, Refino CJ, Badillo JM,ErrettCJ, Zivin JA.Optimized thrombolysis of cerebral clots withtissue-type plasminogen activator in a rabbit model of embolicstroke. JPharmacol Exp Ther. 1993;264:67-73.26. Martin U, Fischer S, Kohnert U, Lill H, Rudolph R, Sponer G,Stern A, Strein K.Properties of anovel plasminogen activator...
متن کاملDesmodus rotundus (Mammalia: Chiroptera) on the southern coast of Rio de Janeiro state, Brazil.
Since the 1990s, attacks by hematophagous bats on humans and domestic animals have been reported both on the continent and on the islands on the southern coast of Rio de Janeiro state. The density of vampire bats was investigated based on percentage of captures during control of Desmodus rotundus samplings and during bat diversity research. In the present work, 203 individuals of D. rotundus we...
متن کاملCoronary thrombolysis with Desmodus salivary plasminogen activator in dogs. Fast and persistent recanalization by intravenous bolus administration.
BACKGROUND DSPA (Desmodus salivary plasminogen activator) is a new thrombolytic agent corresponding to a natural plasminogen activator discovered in the saliva of the vampire bat Desmodus rotundus. Compared with tissue plasminogen activator (TPA), DSPA, produced in a recombinant cell line, is more fibrin cofactor dependent than TPA. METHODS AND RESULTS The thrombolytic properties of DSPA and ...
متن کاملDesmodus rotundus and Artibeus spp. bats might present distinct rabies virus lineages.
In Brazil, bats have been assigned an increasing importance in public health as they are important rabies reservoirs. Phylogenetic studies have shown that rabies virus (RABV) strains from frugivorous bats Artibeus spp. are closely associated to those from the vampire bat Desmodus rotundus, but little is known about the molecular diversity of RABV in Artibeus spp. The N and G genes of RABV isola...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1996
ISSN: 0021-9258
DOI: 10.1074/jbc.271.13.7381